Three novel canine genes for Caffey, Raine and van den Ende-Gupta syndromes have been discovered by investigators. Research reveals close similarities of the canine models of human rare disorders and highlights the potential of comparative research approach for the development of rare disease diagnostics and treatments. Gene discoveries will benefit also veterinary diagnostics and breeding programs.
A contagious form of cancer that can spread between dogs during mating has highlighted the extent to which dogs accompanied human travelers throughout our seafaring history. But the tumors also provide surprising insights into how cancers evolve by 'stealing' DNA from their host.
Canine Degenerative Myelopathy (DM) is a neurodegenerative disease in dogs with similarities to ALS in humans. Scientists have discovered a modifier gene that affects the risk of developing DM in Pembroke Welsh Corgis (PWC).